Doctors give unbiased, trusted information on whether Levaquin can cause or treat Rash: Dr. Ahrendsen on levaquin rash picture: Usually doesn't look like a friction rash or rash from razor burn, but they can appear atypical. It is best to have a knowledgeable provider look at it. One look is worth 1000 words. I was prescribed Levaquin recently for a prostate infection. During the course of taking the antibiotic, I developed an acne-like reaction on my entire forhead. it has been two months since the reaction and the condition has not dimininshed. Precautions. Drug information provided by: IBM Micromedex. It is very important that your doctor check your or your child's progress while using this medicine. About a two years ago I started getting a skin rash near my ankle after taking levaquin. I mention it to my doctor and was told it was pupura. I went to a vascular doctor and was tested. Levaquin is the brand name for levofloxacin. It's an antibiotic that treats a variety of bacterial infections. Common side effects are dizziness, rash, flatulence (farting), itching, and problems sleeping. Levaquin has serious side effects so talk to your doctor or pharmacist before taking this drug. I haven't had any break out of the rash in months but I don't feel any better.being on the rifampin and levaquin totally stopped the rashes from appearing. Levaquin Rash, allergic to sulfa, sulfer, preservative, pharmacist I have taken 5 doses. Today I.I am allergic to sulfa , and this is the same rash I would get from it. What should I discuss with my healthcare provider before taking levofloxacin (Levaquin, Levaquin Leva-Pak)? You should not use this medicine if you are allergic to levofloxacin or other fluoroquinolones (ciprofloxacin, gemifloxacin, moxifloxacin, norfloxacin, ofloxacin, and others). I had a sinus infection and was put on Levaquin. I got rashes all over and my dr said I probably had an allergic reaction to it so I stopped taking it. levaquin I have rashes mostly in my leg that itches from time to time. I started as a small red rash at the penis then to the inner thighs and to the legs.It's been around 3 months since my sexual encounter w a woman but 100% I use condom but I dont know how it transmitted.